SVI Huygens 26.04 is the latest major release of Scientific Volume Imaging’s microscopy image restoration and analysis software. This update introduces Cellpose 3D for AI-powered segmentation, significant performance improvements, and enhanced analysis tools.
🆕 Key New Features in 26.04
Cellpose 3D Integration: The headline feature is the integration of Cellpose 3D, expanding Huygens’ AI segmentation capabilities for 3D datasets. This allows users to perform quantitative object analysis using state-of-the-art deep learning segmentation within the same environment, with easy comparison between classical and AI methods.
Enhanced ROI & Analysis Options: New ROI options allow colocalization analysis per ROI element (e.g., per cell), enabling more granular and biologically relevant measurements.
Improved File Format Support: Bioformats-compatible Huygens HDF5 now supports Pyramid HDF5 compatibility with Bioformats/BDV, improving interoperability with other imaging tools.
Performance Enhancements: The Stitcher has received a drastic speed improvement, and vignetting correction is significantly faster.
Visualization Improvements: New free camera movement allows users to navigate around and through 3D objects more naturally for better inspection.
📊 Core Capabilities
Huygens remains the industry-standard platform for image restoration and analysis:
| Category | Capabilities |
|---|---|
| Deconvolution | CMLE, GMLE, Quick Maximum Likelihood, Deconvolution Express, PSF Distiller |
| AI Tools | Cellpose 3D, Hybrid AI Deconvolution, SAM2-powered segmentation |
| Visualization | Twin Slicer, MIP, SFP Renderer, 3D visualization |
| Analysis | Object Analyzer, Colocalization Analyzer, ROI-based analysis |
| Automation | Batch Processor, Workflow Processor, Python/Tcl scripting |
