Analyst 1.7.4 is a point release of SCIEX’s Analyst software, a comprehensive mass spectrometry platform for data acquisition, processing, and analysis in LC/MS workflows. It supports SCIEX QTRAP®, triple quadrupole, and TripleTOF® systems, enabling precise detection and quantitation of small and large molecules in regulated and non-regulated environments. This version builds on Analyst 1.7.3, incorporating hotfixes for stability, hardware compatibility, and workflow efficiency. Released in April 2025, it addresses ongoing transitions toward SCIEX OS software, with end-of-support for Analyst planned in the coming years.
Key Features of Analyst 1.7.x Series (Including 1.7.4)
- Data Acquisition and Control: Intelligent methods for IDA (Information-Dependent Acquisition), MRM (Multiple Reaction Monitoring), and MS/MS scanning, with support for automated optimization and real-time monitoring.
- Processing and Analysis: Advanced quantitation tools (e.g., MQ IV algorithm), peak integration, and scripting for custom workflows; handles WIFF data from SCIEX 7500+ systems acquired via SCIEX OS.
- Reporting and Compliance: Audit trail management, PDF exports, and templates with new tags for UV/DAD channels; supports 21 CFR Part 11 compliance in regulated labs.
- Hardware Integration: Drivers for Shimadzu LC-40/20/30, ExionLC 2.0, and new Instrument Control Board (ICB-5) for SCIEX 3500–6500+ systems.
- Security: Mixed-mode security with unlock/logout features, role-based access, and integration with Microsoft Active Directory.
Recent Updates in 1.7.4
This release focuses on refinements for reliability and compatibility:
- New Features:
- Instrument model/serial in optimization reports.
- Batch validation warnings for Shimadzu LC-40 plate changers.
- Read-only access for QA reviewers on shared Results Tables.
- No password length limits (aligned with Windows).
- New reporter tags for ADC_UV channels and DAD data.
- WIFF data processing from SCIEX OS on 7500+ systems.
- Enhancements (Incorporating HotFix 1–3 from 1.7.3):
- PDF export for audit trails (read/write users only).
- ICB-5 support for multiple SCIEX systems.
- OptiFlow Turbo V ion source voltage retention between runs.
- Windows 10 21H2/22H2 support; updated LC drivers and sMRM calculator.
- VICI Valco 10-port valve support; Microsoft Office 2021 compatibility.
- New plate layouts for Shimadzu autosamplers; ExionLC firmware/driver updates.
- Deployment tool for AAC security databases.
