HSPiP 6.1.02 is the current version of Hansen Solubility Parameters in Practice (HSPiP), a specialized software package developed by Steven Abbott and collaborators for predicting and analyzing the solubility, dispersion, diffusion, and compatibility of materials—particularly polymers, solvents, nanoparticles, and chemicals—using Hansen Solubility Parameters (HSP). HSP theory breaks down solubility behavior into three components: dispersive (δd), polar (δp), and hydrogen-bonding (δh) energies, allowing users to model interactions quantitatively (e.g., via the relative energy difference, RED, where RED < 1 indicates good solubility).
Key Features
- Datasets: Includes extensive databases like the official solvents dataset (with experimental HSP values and thermochemical data), the “10K” solvents dataset (YMB-based calculations for ~10,000 chemicals), and polymer databases for commercial materials.
- Tools and Modules:
- Solvent Optimizer: Identifies optimal solvents or blends for a target material by plotting solubility spheres in 3D HSP space.
- Predictive Modeling: Uses algorithms like YMB (Yamamoto Molecular Break) for estimating HSP from molecular structures when experimental data is unavailable.
- Applications: Supports formulation in industries such as coatings, adhesives, pharmaceuticals (e.g., drug solubility prediction), cosmetics, food science, printed electronics, and chromatography method development.
- eBook Integration: Comes bundled with an interactive eBook (PDF) explaining HSP theory, examples, and case studies by Steven Abbott and Charles M. Hansen.
- Visualization: 3D sphere plots, solubility spheres, and exportable data for reports or further analysis.
- System Requirements: Windows 64-bit (Windows 10+), requires .NET Framework 4.6. Installs to Program Files/Hansen-Solubility-6, with data files in My Documents/HSPiP Data.
